Construction of enterovirus strains using reverse genetic platform
Technology Introduction:
Technology Introduction:Reverse genetics is an important recombinant DNA technology used to study the function of RNA viral genes. This technology can be used to create full-length, infectious cDNA clones of enteroviruses, generating pure enterovirus strains and avoiding the quasispecies resulting from errors in RNA virus replication. Alternatively, mutant strains can be generated through point mutations to study the characteristics caused by enterovirus gene mutations.
Industry Applicability:
This project develops a technology platform for bioeconomy to assist and support the local bio-industry in developing the emerging enterovirus vaccines, thereby promoting the development of the local pharmaceutical and biotechnology industry.
Industrial Applications:
-
National Health Research Institutes
National Health Research Institutes (NHRI) is a medical and health research organization in Taiwan, established as a public-funded foundation. Its main research areas include medicine, pharmaceuticals, public health, and other life sciences, as well as related technologies such as vaccine development.
