The product “Cloud AIoT Aquaculture Water Quality Monitoring Tracking Pre-warning and Non-toxic Solutions” has been awarded a National Invention Patent. The system has won more than 25 innovative competition awards, including the CES2019 Award, Smart Agriculture Award, Smart City Award, National Innovation Research Award, and so on. The core technology of the system design is the trans-disciplinary multiple technologies of cloud, AIoT, mobile technology, and the integration of software and hardware design. The aim mission is to make the water parameters clear to terminate the phenomenon of blind aquaculture farming, which will, therefore, reduce the farming cost and waste of precious water and electric power resources. The seafood safety for people’s health and environmental sustainability are the main visions of the product research and development. The product is a pioneer in non-toxic aquaculture farming by tracking the resources of toxic concentration and Vibrio during aquaculture farming. The main functions include quick monitoring, tracking, and predicting the change of water parameters, especially the toxic concentration and Vibrio. The product also provides information about the resources of toxic concentration and Vibrio, which is the basis of non-toxic solutions to solve the toxic problems.