Method and composition for decreasing the psychotomimetic side effect and addictive disorder of ketamine
The present invention relates to a method for decreasing the abuse liability and psychotomimetic side effects and enhancing the antidepressant-like effects of ketamine by the combination of ketamine with a methyl glycine derivative. The combination can be applied in the treatment of treatment-resistant depression/bipolar disorders, anxiety disorders and pain.
National Health Research Institutes (NHRI) is a medical and health research organization in Taiwan, established as a public-funded foundation. Its main research areas include medicine, pharmaceuticals, public health, and other life sciences, as well as related technologies such as vaccine development.
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