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Development of Critical Raw Materials for Advanced mRNA Production

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Development of Critical Raw Materials for Advanced mRNA Production

This technology focuses on developing a patented 5' cap analog (ITRI-Cap), a critical component in mRNA drug production, aiming to bypass existing international patents. It also integrates an advanced one-pot in vitro transcription (IVT) process. Compared to CleanCap®, ITRI-Cap offers simplified synthesis, improved translation efficiency, and reduced production costs. The solution reduces reliance on imported raw materials and high licensing fees, providing CDMO manufacturers with a competitive and flexible alternative, while reinforcing Taiwan’s position in the nucleic acid supply chain.

Industrial Technology Research Institute

ITRI is a world-leading applied technology research institute with more than 6,000 outstanding employees. Its mission is to drive industrial development, create economic value, and enhance social well-being through technology R&D. Founded in 1973, it pioneered in IC development and started to nurture new tech ventures and deliver its R&D results to industries. ITRI has set up and incubated companies such as TSMC, UMC, Taiwan Mask Corp., Epistar Corp., Mirle Automation Corp., and Taiwan Biomaterial Co.

Contact

  • Name:Ming-Hsi Wu

  • Phone:(03)5732575

  • Address:195, Sec. 4, Chung Hsing Rd., Chutung, Hsinchu, Taiwan 31040, R.O.C.

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Other Information

  • Pavilion:Innovation Economy Precision Health ID20

  • Affiliated Ministry:Department of Industrial Technology,MOEA

  • Application Field:Biotechnology & Medical care

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  • Technology maturity:Mass production

  • Exhibiting purpose:Technology transactions、Product promotion、Display of scientific results

  • Trading preferences:Negotiate by self

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