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Development of a Mesenchymal Stem Cell Platform for Multi-Gene Precision Delivery: A Novel Strategy for Cross-Cancer Precision Immunotherapy

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Development of a Mesenchymal Stem Cell Platform for Multi-Gene Precision Delivery: A Novel Strategy for Cross-Cancer Precision Immunotherapy

Technology Introduction:
This platform introduces a non-viral gene delivery system using umbilical mesenchymal stem cells (UMSCs) engineered via electroporation to carry multiple therapeutic genes. UMSCs' low immunogenicity and tumor-tropic properties enable targeted delivery to solid tumors, achieving both tumor suppression and immune modulation. The approach offers high safety, scalability, and off-the-shelf potential, representing a next-generation strategy for gene and cell-based cancer therapy.
Industry Applicability:
This platform targets hard-to-treat solid tumors using off-the-shelf UMSCs with non-viral multi-gene delivery, offering high safety, stable expression, and tumor targeting. It supports applications in regenerative medicine, biotech, immunotherapy, and precision medicine. With scalable manufacturing, global patent coverage, and strong translational value, it offers a differentiated solution for next-generation cancer gene and cell therapy.

China Medical University

Currently, there are nine colleges, including the College of Medicine, College of Dentistry, College of Pharmacy, College of Traditional Chinese Medicine, College of Public Health, College of Health Care, College of Life Sciences, College of Humanities and Technology, and College of Medical Engineering, including 23 bachelor's programs, 34 master's programs, 20 doctoral programs, and teaching, research, and medical units such as the Taichung Affiliated Hospital, Beigang Affiliated Hospital, Hsinchu Affiliated Hospital, Children's Hospital, and Tainan Municipal Annan Hospital (commissioned to be built and operated by China Medical University). The university is well-equipped with various research and medical facilities, of which about 70% are related to Chinese and Western medicine. It provides the most complete curriculum in the country with the characteristics of the integration of Chinese and Western medicine, cultivates medical, nursing, pharmaceutical, and technical professionals with the characteristics of the integration of Chinese and Western medicine, and develops the three most Chinese medicine-based fields, including the development of Chinese medicine resources, the research and development of Chinese medicine health foods and anti-disease drugs, and the theory and application of Chinese medicine (including acupuncture). After nearly half a century of intensive cultivation, the university has developed into an excellent institution of higher education in the country and even the world with the most Chinese and Western medicine-based integration characteristics, and has gradually implemented the scientification, modernization, and internationalization of Chinese medicine, as well as pioneered the emerging medicine that combines Chinese and Western medicine.

Contact

  • Name:

  • Phone:03-422-7151 #65085

  • Address:91,Hsueh-Shih Road, Taichung,404, Taiwan,Republic of China

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Other Information

  • Pavilion:Future Tech Bio-tech, New Drugs & Medical Devices FM18

  • Affiliated Ministry:National Science and Technology Council

  • Application Field:Biotechnology & Medical care

Location More info

Patent

  • I723354

    • Patent Name
    • Application Country
    • Patent type
    • Assignee
    • Application Number
    • Publish Number
    • Patent Name

      用於癌症治療之工程化幹細胞

    • Application Country

      Taiwan

    • Patent type

      Utility Invention

    • Assignee

      中國醫藥大學

    • Application Number

      TW108109124

    • Publish Number

      I723354

Website & Links

  • Technology maturity:Others

  • Exhibiting purpose:Display of scientific results

  • Trading preferences:Negotiate by self

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