NIR-II fluorescence ＋ photoacoustic dual-modality 3D small animal imaging system combined with self-made fluorescence/photoacoustic polymer dots for whole body and tumor blood vessel imaging
1. We developed a NIR-II fluorescence ＋ photoacoustic 3D small animal dual-modality imaging system to visualize 3D whole body and tumor blood vessel images in mice. Our system is suitable for cancer monitoring research and pharmacokinetic analysis.
2. We developed a 3D blood vessel reconstruction algorithm, integrating NIR-II fluorescence and photoacoustic imaging to visualize the 3D tumor blood vessels, with an imaging depth of 10 mm, an image resolution of 50 um, and a depth resolution of 100 um.
3. The self-made fluorescent/photoacoustic polymer dots in the NIR-II region has the advantages of strong light absorption, good photostability, and low biological toxicity.
National Yang Ming Chiao Tung University (NYCU) was formed in 2021 through the merger of National Yang Ming University and National Chiao Tung University. Located in Hsinchu, Taiwan, NYCU is a leading institution specializing in technology, engineering, medicine, and social sciences. The university is known for its strengths in research and innovation, particularly in areas such as information technology, biomedicine, and artificial intelligence. NYCU fosters interdisciplinary collaboration, global partnerships, and aims to nurture professionals with strong academic foundations and leadership skills to address societal challenges and contribute to technological advancements.
Technology maturity：Experiment stage
Exhibiting purpose：Display of scientific results
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