AI-Guided Phenotypic Response Surface Platform for Personalized Dose Navigation and Multimodal Therapy Optimization
Technology Introduction:
This platform integrates human cell models, zebrafish disease models, and AI-guided phenotypic response surfaces to optimize multidrug combinations and dose regimens under efficacy and safety constraints. It generates interpretable optimized dose windows to support personalized dose navigation and preclinical decision-making.
Industrial Applications:
Applications include new drug and combination therapy development, drug repurposing, precision dosing, and dose optimization for health products and precision nutrition. The current platform is positioned for preclinical and research use and B2B collaboration, with planned progression toward clinical validation, including N-of-1 studies, and future clinical decision-support development.
National Health Research Institutes
National Health Research Institutes (NHRI) is a medical and health research organization in Taiwan, established as a public-funded foundation. Its main research areas include medicine, pharmaceuticals, public health, and other life sciences, as well as related technologies such as vaccine development.
Contact Information
Name：Chiou-Hwa Yuh
Tel：037-206-166 #35338
Address：35 Keyan Road, Zhunan, Miaoli County 35053, Taiwan
