One Model Fit All: Revolutionary One-Stop Shop System for Predicting Co ronary Stenosis without Normal Database in Myocardial Perfusion Imagin g

Meeting & Discussion

This technology offers an automated system and method to preprocess M
PI and use DL models to predict significant coronary artery disease (CAD).
The preprocessing includes automated segmentation of the myocardial re
gion, automatic registration to a template, activity normalization, and sph
erical coordinate transformation. These techniques enable three-dimensio
nal (3D) image analysis and prediction by the deep learning (DL) model, w
hich overcomes the orientation problem for 3D myocardial structures with
convolutional neural networks. Validated through cross-validation with ne
arly a thousand clinical scans and external validation with nearly a thousa
nd additional cases, the technology surpasses traditional total perfusion d
eficit (TPD) prediction, achieving an area under the receiver operating cha
racteristic curve of 0.844 compared to TPD's 0.759, while maintaining th
e same specificity and increasing sensitivity from 76.6% to 83.8%. Importa
ntly, this technology does not relay on a normal database, avoiding the ti
me-consuming step of collecting data from healthy subjects.

Far Eastern Memorial Hospital

There was a large population during the 70's and 80's in Banqiao and Tuchen District, New Taipei City; however, there was not any modern hospital in these areas. Therefore, the seriously injured workers and ‘in critical condition’ patients had to transfer to Taipei City. Under this circumstance, many of them were delayed in receiving a proper medical treatment due to the long traveling distance. Mr. Yu-Ziang Hsu, founder of the Far Eastern Group, was aware of the situation and had based on his belief of "By the society, for the society" having Far Eastern Memorial Foundation setup for the construction of hospital, emergency rescue, free clinic for the poor and sick, and inspiring medical and medicine research. Far Eastern Memorial Hospital (FEMH) was established in Banqiao on April 1, 1981 and with 150 beds ready for service. FEHM was accredited by the Ministry of Education as the secondary teaching hospital to be in 1983, the secondary teaching hospital in 1985, district hospital in 1988, district hospital & teaching hospital in 1991 to 1997, and district hospital and Class II Teaching Hospital in 2000 to 2003.