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An Oral AR/AR-V7 PROTAC for the Treatment with Castration-Resistant Prostate Cancer (CRPC)

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An Oral AR/AR-V7 PROTAC for the Treatment with Castration-Resistant Prostate Cancer (CRPC)

An oral bioavailable PROTAC drug targeting both AR and AR-V7 for the treatment of castration-resistant prostate cancer (CRPC) was developed by Industrial Technology Research Institute. This innovative drug effectively degrades AR and AR-V7 proteins within prostate cancer cells, resulting in the inhibition of castration-resistant tumor growth. The preclinical toxicology study has demonstrated the drug's favorable safety profile, highlighting its potential as a novel protein degradation drug. ITRI's oral bioavailable AR/AR-V7 PROTAC drug represents a significant advancement in the field of prostate cancer treatment and offers a promising therapeutic option for patients with CRPC.

Features & Specifications:
・Targeted protein degradation capability
・Superior effectiveness compared to approved drugs
・Low adverse effects and high safety

Industrial Technology Research Institute

ITRI is a world-leading applied technology research institute with more than 6,000 outstanding employees. Its mission is to drive industrial development, create economic value, and enhance social well-being through technology R&D. Founded in 1973, it pioneered in IC development and started to nurture new tech ventures and deliver its R&D results to industries. ITRI has set up and incubated companies such as TSMC, UMC, Taiwan Mask Corp., Epistar Corp., Mirle Automation Corp., and Taiwan Biomaterial Co.

Contact

  • Name:Juno Chen

  • Phone:

  • Address:195, Sec. 4, Chung Hsing Rd., Chutung, Hsinchu, Taiwan 31040, R.O.C.

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Other Information

  • Pavilion:Innovation Pilot Discovering Technology Treasures IA64

  • Affiliated Ministry:Department of Industrial Technology,MOEA

  • Application Field:Biotechnology & Medical care

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Website & Links

  • Technology maturity:Prototype

  • Exhibiting purpose:Technology transactions、Display of scientific results

  • Trading preferences:Technical license/cooperation

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