Taiwan is located on the Pacific Rim Seismic Belt, which is an active area of earthquakes. Due to the threat of earthquakes that has endangered public safety severely, the research team is committed to developing “Structural Safety Quick Screening System,” which is both reliable and efficient. The developed method performs entropy analysis on the microvibration signal of structures and combine the analysis results with artificial intelligence. By building a database through practical measurement and numerical simulation, and the training of neural network in artificial intelligence, this study can not only accelerate the prevailing of structural health monitoring, but also ensure the safety of people.