The present invention discloses a vascular bone organoid and its compression perfusion fabricator system. The compression-perfusion fabricator system includes a compression device, a culture tank, a perfusion device, and a microcomputer driver. The compression device and the perfusion device are controlled and adjusted through the microcomputer driver to provide dynamic mechanical compression and perfusion stimulation simultaneously. The system simulates the dynamic microenvironment within the human body. The present invention further utilizes 3D bioprinting technology to manufacture a vascular bone organoid, which is cultured in the compression-perfusion fabricator system, to mimic the growth of bone and vascular endothelial cells within the normal dynamic physiological environment of the bone marrow cavity.
大專院校
Name:Jia-Fwu Shyu
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Address:No.161, Minquan E. Rd., Sec. 6, Neihu, Taipei, 11490, Taiwan
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